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Estrogen Sulfotransferase Rabbit pAb (bs-0629R)  
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產(chǎn)品編號 bs-0629R
英文名稱 Estrogen Sulfotransferase Rabbit pAb
中文名稱 雌激素硫酸轉(zhuǎn)移酶抗體
別    名 Estrogen Sulfotransferase; Ste; SULT1E1; Estrogen sulfotransferase, testis isoform; Sulfotransferase, estrogen-preferring; EST; EST1; STE; sulfotransferase family 1E, estrogen-preferring, member 1; Sulfotransferase estrogen preferring; ST1E1_HUMAN.  
研究領(lǐng)域 免疫學(xué)  生長因子和激素  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat,Rabbit,Pig,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 32 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Estrogen Sulfotranferase: 51-145/294 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure(number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.

Function:
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Liver, intestine and at lower level in the kidney.

Similarity:
Belongs to the sulfotransferase 1 family.

SWISS:
P49888

Gene ID:
6783

Database links:

Entrez Gene: 6783 Human

Entrez Gene: 25355 Rat

Omim: 600043 Human

SwissProt: P49888 Human

SwissProt: P52844 Rat

Unigene: 479898 Human



產(chǎn)品圖片
Sample: HepG2(Human) Cell Lysate at 30 ug Primary: Anti-Estrogen Sulfotransferase (bs-0629R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kD Observed band size: 32 kD
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