| 產(chǎn)品編號 | bs-0848R |
| 英文名稱 | Rabbit Anti-CSP antibody |
| 中文名稱 | 環(huán)子孢子蛋白(約氏瘧原蟲)抗體 |
| 別 名 | circumsporozoite protein(Plasmodium yoelii); Circumsporozoite protein; CS; CSP_PLAYO. |
| 研究領(lǐng)域 | 昆蟲 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Plasmodium yoelii) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 37 kDa |
| 檢測分子量 | |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from the middle of Plasmodium yoelii CSP: 101-200/367 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
No data available. Function: The circumsporozoite protein is the immunodominant surface antigen on the sporozoite (the infective stage of the malaria parasite that is transmitted from the mosquito to the vertebrate host). Similarity: Belongs to the plasmodium circumsporozoite protein family. Contains 1 TSP type-1 domain. Database links:
SwissProt: P06914 Plasmodium yoelii yoelii
瘧原蟲的保護性抗原主要在蟲體表面，統(tǒng)稱表面抗原。在瘧原蟲生活史的發(fā)育各期，既有共同抗原，又有期特異性抗原，近年來經(jīng)研究發(fā)現(xiàn)了惡性瘧原蟲和間日瘧原蟲的配子表面的保護性抗原，已證明成熟子孢子體外附著的環(huán)子孢子蛋白（Circumsporozoite protein，CSP）具有明顯的抗原性。 紅內(nèi)期瘧原蟲的不同發(fā)育階段，其抗原的質(zhì)和量均有變化，并可在被寄生的紅細胞膜上表露出來。裂殖子和子孢子均屬游離的瘧原蟲，因此誘導(dǎo)的宿主免疫均較明顯。已知有許多瘧原蟲抗體可作用于裂殖子，使裂殖子凝集，阻止裂殖體釋放裂殖子。裂殖子表面抗原與其侵入紅細胞有關(guān)。 |
