| 產(chǎn)品編號(hào) | bs-0239R |
| 英文名稱 | HIV gp41 Rabbit pAb |
| 中文名稱 | 艾滋病病毒抗體 |
| 別 名 | HIV1 gp41; HIV-1 gp41; HIV1gp41; HIVgp41; Transmembrane protein gp41; Glycoprotein 41; Human Immunodeficiency Virus 1; HIV1 ENV(gp160); HIV1 gp160; HIV1gp160; HIV-1 gp160; env; Env polyprotein; Envelope glycoprotein gp160; Glycoprotein 41; gp41; HIV1; HIV |
| 研究領(lǐng)域 | 細(xì)菌及病毒 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: HIV) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39/93 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Transmembrane protein gp41: 1-80/120 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
Database links: SwissProt: Q79670 Human immunodeficiency virus 人類免疫缺陷病毒Ⅰ型(HIV-1)的包膜糖蛋白gp120、gp41 HIV感染后可刺激機(jī)體生產(chǎn)囊膜蛋白（Gp120,Gp41）抗體 病毒呈球形，直徑100～120nm，電鏡下可見(jiàn)一致密的圓錐狀核心，內(nèi)含病毒RNA分子和酶（逆轉(zhuǎn)錄酶、整合酶、蛋白酶），病毒外層囊膜系雙層脂質(zhì)蛋白膜，其中嵌有g(shù)p120和gp41，分別組成刺突和跨膜蛋白。 |
