| 產(chǎn)品編號 | bs-0597R |
| 英文名稱 | DPPA2 Rabbit pAb |
| 中文名稱 | 多能發(fā)育相關(guān)基因2抗體 |
| 別 名 | Developmental Pluripotency Associated 2; developmental pluripotency associated gene2; PESCRG1; Pluripotent embryonic stem cell related protein 1; cancer/testis antigen 100; CT100; developmental pluripotency-associated gene 2; developmental pluripotency-as |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 34 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DPPA2: 211-301/301 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
SCRG1 (scrapie-responsive protein 1) is a 98 amino acid secreted protein that belongs to the SCRG1 family. The SCRG1 protein contains a 20-amino acid signal peptide, and is expressed abundantly in the central nervous system of human adult, but not at all in fetal brain. The protein is targeted to the Golgi apparatus and large dense-core vesicles/secretory granules in neurons. High levels of SCRG1 transcripts are also observed in testis and aorta. SCRG1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The SCRG1 protein may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. The human and mouse SCRG1 proteins share 83% sequence identity. The SCRG1 gene is conserved in chimpanzee, cow, mouse, rat and chicken, and maps to human chromosome 4q34.1. Function: Dppa2 is a SAP domain protein expressed only in pluripotent cells and the developing germ line. Subcellular Location: Secreted. Tissue Specificity: Expressed abundantly in the central nervous system of adult, but not at all in fetal brain. High levels of SCRG1 transcripts are also observed in testis and aorta. Similarity: Belongs to the SCRG1 family. SWISS: Q7Z7J5 Gene ID: 151871 Database links: Entrez Gene: 151871 Human Entrez Gene: 73703 Mouse Omim: 614445 Human SwissProt: Q7Z7J5 Human SwissProt: Q9CWH0 Mouse Unigene: 351113 Human Unigene: 27857 Mouse |
