| 產(chǎn)品編號(hào) | bsm-62922R |
| 英文名稱(chēng) | NRAS Recombinant Rabbit mAb |
| 中文名稱(chēng) | 原癌基因N-Ras重組兔單抗 |
| 別 名 | GTPase HRas; GTPase KRas; GTPase NRas; H-Ras-1; HAMSV; HRAS; HRAS1; K-RAS; N-RAS; NRAS; p21ras; RASH1; RASK2; Transforming protein p21. |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Recombinant |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-1:2000,Flow-Cyt=1:20-1:100,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 21 kDa |
| 檢測(cè)分子量 | 18 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NRAS |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. SWISS: P01111 Gene ID: 4893 細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)系統(tǒng)紊亂是腫瘤細(xì)胞生長(zhǎng)的重要特征之一，Ras蛋白參與體內(nèi)多種細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)途徑而發(fā)揮作用,而原癌基因N-ras是一種多功能的細(xì)胞因子，廣泛存在于自然界，N-ras在多種細(xì)胞生命活動(dòng)中起極為重要的作用，包括細(xì)胞的增殖、分化和細(xì)胞骨架的構(gòu)建等等，該抗體主要用于腫瘤方面的研究。 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with NRAS monoclonal antibody, unconjugated (bsm-62922R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
|
