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產(chǎn)品編號	bsm-62888R
英文名稱	LRP6 Recombinant Rabbit mAb
中文名稱	低密度脂蛋白受體相關蛋白6重組兔單抗
別名	LRP6
抗體來源	Rabbit
克隆類型	Recombinant
交叉反應	Human
產(chǎn)品應用	WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
理論分子量	180 kDa
檢測分子量	180-230
性狀	Liquid
免疫原	KLH conjugated synthetic peptide derived from human LRP6
亞型	IgG
純化方法	affinity purified by Protein A
緩沖液	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
保存條件	Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事項	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
產(chǎn)品介紹	Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. SWISS: O75581 Gene ID: 4040
產(chǎn)品圖片	25 ug total protein per lane of various lysates (see on figure) probed with LRP6 monoclonal antibody, unconjugated (bsm-62888R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.