| 產(chǎn)品編號 | bsm-62861R |
| 英文名稱 | Phospho-GLUT4 (Ser488) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化葡萄糖轉(zhuǎn)運蛋白4重組兔單抗 |
| 別 名 | insulin-responsive; Glucose transporter GLUT 4; Glucose transporter type 4; Glucose transporter type 4 insulin responsive; GLUT4; Insulin responsive glucose transporter type 4; SLC2A4; Solute carrier family 2 member 4. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 55 kDa |
| 檢測分子量 | 45 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GLUT4 around the phosphorylation site of S488 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell. SWISS: P14672 Gene ID: 6517 葡萄糖轉(zhuǎn)運蛋白-4是一種十分重要的葡萄糖轉(zhuǎn)運體,與胰島素抵抗和2型糖尿病密切相關(guān).葡萄糖轉(zhuǎn)運蛋白4在細胞內(nèi)部和細胞膜之間循環(huán)流動.實現(xiàn)對葡萄糖的轉(zhuǎn)運需要葡萄糖轉(zhuǎn)運蛋白4自身的轉(zhuǎn)位和活化.葡萄糖轉(zhuǎn)運蛋白4與肥胖、腫瘤相關(guān)聯(lián). GLUT-2和GLUT-4蛋白這兩個葡萄糖運載體的研究對于糖尿病的胰島素釋放障礙和胰島素抵抗有重要意義. |
| 1、抗體溶解方法 | |
| 2、抗體修復(fù)方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關(guān)于肽鏈的設(shè)計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
