| 產(chǎn)品編號 | bsm-61270R |
| 英文名稱 | HMBS Recombinant Rabbit mAb |
| 中文名稱 | 卟膽原脫氨酶重組兔單抗 |
| 別 名 | UPS; PBGD; PORC; PBG-D; HMBS; Hydroxymethylbilane synthase. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39 kDa |
| 檢測分子量 | 42 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Porphobilinogen deaminase |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
As part of the heme biosynthetic pathway, catalyzes the sequential polymerization of four molecules of porphobilinogen to form hydroxymethylbilane, also known as preuroporphyrinogen. SWISS: P08397 Gene ID: 3145 卟膽原脫氨酶，為血紅素等四吡咯環(huán)化合物合成通路中的催化酶。PBGD催化卟膽原(Porphobilingen，PBG)底物的線性四聚化，反應(yīng)過程中四分子卟膽原底物有序性的共價連接到酶的輔基上，最后水解形成具有四聯(lián)吡咯環(huán)結(jié)構(gòu)的尿卟啉原前體。PBGD的活力缺陷會引起急性間歇性卟啉癥(Acute Intermittant Porphyria，AIP)的發(fā)生。 |
| 產(chǎn)品圖片 |
Western blot analysis of HepG2 cell lysate. Using HMBS (bsm-61270R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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