| 產(chǎn)品編號 | bsm-61098R |
| 英文名稱 | CD24 Recombinant Rabbit mAb |
| 中文名稱 | CD24重組兔單抗 |
| 別 名 | CD24; CD24 antigen; CD24A; HAS; Signal transducer CD24. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 8 kDa |
| 檢測分子量 | 31-45 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD24 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. SWISS: P25063 Gene ID: 100133941 神經(jīng)干細(xì)胞標(biāo)志物 腫瘤標(biāo)志物 CD24是一種低分子質(zhì)量高度糖基化的黏附分子, 主要表達(dá)在造血系統(tǒng). 最近研究表明, 在造血系統(tǒng)腫瘤和一些器官的實體瘤表面可見CD24高表達(dá)。 近幾年很多學(xué)者認(rèn)為：CD24在前列腺癌、非小細(xì)胞肺癌、鼻咽癌、原發(fā)性肝細(xì)胞癌、膽管細(xì)胞癌、麥克爾細(xì)胞癌、神經(jīng)源性腫瘤、胰腺癌、胃癌、結(jié)腸癌、腎細(xì)胞癌、B細(xì)胞淋巴瘤、乳腺癌等腫瘤組織中表達(dá)增強, 且和腫瘤侵襲轉(zhuǎn)移、復(fù)發(fā)和預(yù)后相關(guān)。 |
| 產(chǎn)品圖片 |
Western blot analysis of SH-SY5Y cell lysate. Using CD24 (bsm-61098R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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